Greek grandmothers never called them medicinal herbs. Chamomile was for a crying baby's mother, mountain tea for a cold, sage for a sore throat, dittany for a bad stomach. Many of those kitchen remedies are now reviewed by European regulators, and a few have been tested in good clinical trials. This guide lists 13 Greek and Mediterranean medicinal herbs and their uses, sorted by what you want help with. For each one it shows what the evidence actually says, how to use it, and the caution that matters most.
Key takeaways
- What they are: plants used for health rather than only for flavour. In the U.S. herbal teas are sold as foods or supplements, not approved medicines.
- Evidence varies a lot: peppermint oil, saffron and St John's wort have trial evidence. Most others, like chamomile and mountain tea, rest on long traditional use accepted by the European Medicines Agency.
- Tea is not an extract: many studies use concentrated capsules at doses far higher than a cup of tea.
- Interactions are real: St John's wort taken by mouth can weaken birth control, blood thinners, antidepressants and transplant drugs.
- Pregnancy and children: most herbs haven't been tested in these groups. Ask your doctor first.
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What are medicinal herbs?
A medicinal herb is any plant, or part of a plant, used to support health: leaves, flowers, roots, seeds or resin. People have used them for as long as there are written records, and they're still widely used. Most of the World Health Organization's member states report that their populations use traditional and herbal medicine.1
"Natural" doesn't automatically mean safe or effective. Herbs contain active compounds, which is exactly why they can help and why they can occasionally cause harm or interact with medicines.2 In the U.S., herbal teas and supplements aren't reviewed by the FDA for effectiveness before they're sold. In the European Union, the European Medicines Agency (EMA) publishes monographs on individual herbs that say what each is used for, at what dose, and who should avoid it. We rely on those monographs throughout this guide.
List of medicinal herbs and their uses
These are the Greek and Mediterranean medicinal herbs most people ask about. "Traditional (EMA)" means the EMA accepts at least 30 years of safe use for that purpose, but it hasn't been proven in modern trials.3
| Herb | Traditional use | Evidence | How to use | Key caution |
|---|---|---|---|---|
| Chamomile (Matricaria chamomilla) | Calm, sleep, bloating | Traditional (EMA); small trials for anxiety | Tea, 1–2 tsp flowers | Daisy-family allergy; some drug interactions |
| Lavender (Lavandula angustifolia) | Stress, sleep | Traditional (EMA) for flowers | Tea or in blends | Essential oil internally only with your physician's OK |
| Lemon balm (Melissa officinalis) | Stress, sleep, bloating | Traditional (EMA) | Tea, 1–2 tsp leaves | Adults and over-12s |
| Valerian (Valeriana officinalis) | Sleep | Mixed trial results | Evening tea or capsules | Drowsiness; not with sedatives or alcohol |
| Peppermint (Mentha × piperita) | Cramps, IBS, bloating | Strong for oil capsules in IBS | Tea after meals; oil only as capsules | Can worsen reflux |
| Chios mastic (Pistacia lentiscus) | Indigestion | One good trial; traditional (EMA) | Resin or capsules; tea blends | Not in pregnancy or under 18 |
| Dittany of Crete (Origanum dictamnus) | Stomach upsets, colds | Traditional (EMA); lab studies | Tea, 1–2 g, 3–4 min | Avoid in pregnancy |
| Mountain tea (Sideritis spp.) | Coughs, colds, digestion | Traditional (EMA); one extract trial | Tea, ~2 g per cup | Mint-family allergy |
| Thyme (Thymus vulgaris) | Chesty cough with a cold | Traditional (EMA) | Tea with honey | See a doctor if a cough lasts over a week |
| Greek sage (Salvia fruticosa) | Sore throat, digestion | Traditional; lab studies | Tea, 1–2 g | Not in pregnancy; avoid large amounts |
| Rosemary (Salvia rosmarinus, syn. Rosmarinus officinalis) | Indigestion, circulation | Traditional (EMA) | Tea after meals | Not in pregnancy; gallstones |
| Saffron (Crocus sativus) | Mood | Several small trials of extracts | Threads in tea or food | Supplements: check with a doctor |
| St John's wort (Hypericum perforatum) | Low mood (oral); minor wounds (oil) | Trials for mild–moderate depression | Topical oil on the skin | Oral use interacts with many drugs |
Greek medicinal herbs by goal
For sleep and calm
Chamomile is the gentlest place to start. The EMA recognises it as a traditional remedy for minor digestive complaints and colds, and small studies suggest it may help with generalised anxiety, though evidence for sleep is thin.4,5 Its flavonoid apigenin is the reason researchers are interested. See apigenin in chamomile tea.
Lavender flowers and lemon balm are both accepted by the EMA as traditional remedies for mild stress and to aid sleep. Lemon balm is also listed for bloating.6,7 Valerian root is the most famous sleep herb, but its trial results are mixed, and U.S. sleep specialists don't recommend it for chronic insomnia.8 It's fine as part of a relaxing evening ritual. It's not a sleeping pill.
Our Sleep Tea blends lavender, chamomile, valerian and passionflower. The caffeine-free calm collection is for daytime. For more, read our guide to the best herbs for sleep.
For digestion
Peppermint has the best evidence of any digestive herb. In a meta-analysis of 12 trials, enteric-coated peppermint oil capsules clearly improved IBS symptoms and pain.9 Peppermint tea is milder and much less studied. Chios mastic improved indigestion in 77% of people versus 40% on placebo in a three-week trial.10 Dittany of Crete is accepted by the EMA as a traditional remedy for mild stomach upsets.11
Our Digestion Tea combines dittany, peppermint and rosemary. For the full ranking, read our evidence-graded guide to the best herbs for gut health, and our dittany tea guide.
For cold season
Greek mountain tea (Sideritis) is the country's everyday cold remedy. The EMA lists it for coughs with colds and mild digestive discomfort.12 Thyme is accepted for chesty coughs with colds.13 Sage is traditionally gargled or sipped for a sore throat. The EMA lists common sage for mouth and throat inflammation, though the Greek species hasn't been formally assessed.14 Oregano is often called antimicrobial, but that's from lab studies. Enjoy oregano tea as a warm drink, and take oregano essential oil internally only with your physician's OK.
Start with our Greek mountain tea guide, or try Immune Tea (mountain tea, sage and lemon verbena). No tea prevents colds. See a doctor for high fever, breathlessness or a cough that lasts more than a week.
For focus and mood
Rosemary and sage have been linked with memory since ancient times, and both are being studied for it. The research so far is early, small and mostly done with extracts. We cover it in detail in sage and rosemary tea and memory. The EMA's formal listing for rosemary is for indigestion and minor circulation problems.15
Saffron has more human data than most herbs. A 2018 meta-analysis of seven small randomised trials (316 adults with mild to moderate depression) found saffron extract worked better than placebo and similarly to antidepressants, usually at 30 mg a day for 6–12 weeks. All the trials were done in Iran, and the authors called for larger studies.16 That's encouraging, but depression needs a doctor, and a few threads in a cup of tea are a different dose from a standardised extract. Our saffron herbal teas are made with Krokos Kozanis PDO saffron for flavour and ritual. For a caffeine-free desk cup, Focus Tea blends sage, peppermint and rosemary.
For skin
Several of these herbs have traditional uses on the skin. The EMA accepts chamomile for minor skin inflammation, mastic for minor inflammations and small wounds, and dittany as a wet dressing for minor inflammation and bruises.4,11,17
St John's wort oil, the red macerated oil Greek households keep for minor burns and scrapes, is included in the EMA's traditional-use listing for skin disorders and minor wounds.18 Ours is a topical oil, for the skin only. Patch-test it first, and keep treated skin out of strong sun, because St John's wort can make skin more sensitive to light.19 Don't apply it to deep wounds, and see a doctor for burns that blister or look infected.
How to read the evidence on medicinal herbs
Almost every herb has a study saying it "fights inflammation" or "kills bacteria." Four questions help you tell a useful finding from marketing:
- Was it done in people? Test-tube and animal results are where research starts. Most of them never carry over to humans.
- Was it randomised and controlled? A trial that compares the herb with a placebo, in enough people, is far more reliable than a survey or a before-and-after study. A meta-analysis pooling several good trials is stronger still.
- Was it the same thing you're taking? Many trials use concentrated, standardised extracts. A cup of tea delivers much less of the active compounds.
- Who says so? EMA monographs separate "well-established use" (backed by published clinical evidence) from "traditional use" (at least 30 years of safe use, 15 of them in the EU, with plausible but unproven benefit).3 Most herbal teas fall into the second group, and that's worth knowing.
A traditional remedy with a long, safe record is worth enjoying. It just isn't the same thing as a proven treatment, and good herb shops should tell you which is which.
How to use medicinal herbs safely
Used as teas in normal amounts, the herbs in this guide are very safe for most adults. The problems usually come from high-dose supplements, essential oils taken without medical guidance, and interactions with prescription drugs.2
Drug interactions: St John's wort taken by mouth is the big one. It can weaken birth control pills, warfarin, cyclosporine, some heart, HIV and cancer medicines, seizure medicines and statins, and it can cause serotonin reactions with antidepressants.19 Chamomile may interact with warfarin and cyclosporine.5 Tell your doctor and pharmacist about every herb you take regularly, and before surgery.
Pregnancy and breastfeeding: most herbs haven't been studied in pregnancy. The EMA advises against dittany, mastic, sage, rosemary and mountain tea as remedies during pregnancy and breastfeeding. Ask your doctor or midwife before using any herb medicinally.
Children: many EMA monographs don't recommend these herbs as remedies for under-12s or under-18s, simply because they haven't been tested. Never give honey to babies under 12 months.
Allergies: avoid chamomile if you react to ragweed or daisies, and mint-family herbs (sage, rosemary, thyme, oregano, dittany, mountain tea, lavender, lemon balm) if you react to one of them.
Dose: for most herbal teas, 1–2 g (a heaped teaspoon) per cup, 1–3 cups a day. Use one herb at a time when you start, so you can tell what's working. If a symptom lasts more than one or two weeks, see a doctor instead of adding more herbs.
Essential oils: never swallow them unless a clinician has prescribed an enteric-coated product such as peppermint oil capsules.
How to choose good-quality medicinal herbs
Quality affects both safety and flavour. Contamination and mislabelling are real problems in herbal products, so look for:2
- The Latin name and origin on the label, for example Sideritis scardica, Mount Olympus. "Herbal blend" with no species named is a warning sign.
- Whole leaves and flowers rather than powder. Whole herbs keep their aromatic oils longer.
- Organic certification from a recognised body. Our herbs are EU organic certified by Eurocert (GR-BIO-15).
- A fresh, strong smell when you open the bag. Flat, dusty-smelling herbs are old.
- Honest claims. Be wary of any product that promises to cure, detox or melt fat.
New to Greek herbs? The Single Origin Herbs Sampler lets you taste chamomile, mountain tea, oregano and sage on their own before you choose a blend.
Medicinal herbs FAQ
What are medicinal herbs?
Medicinal herbs are plants, or parts of plants such as leaves, flowers, roots or resin, used to support health. Common Greek examples are chamomile, mountain tea, sage, dittany of Crete and Chios mastic.
What are the most common Greek medicinal herbs?
Mountain tea (Sideritis), Greek sage, chamomile, oregano, thyme, dittany of Crete, rosemary, Chios mastic and saffron are the best known. Most are drunk as herbal teas.
Which medicinal herbs have the best scientific evidence?
Peppermint oil for IBS, saffron extract for mild to moderate low mood, and St John's wort for mild to moderate depression have the most clinical trial evidence. Most other herbs are recognised for traditional use rather than proven in trials.
Are medicinal herbs safe?
As teas in normal amounts, most are safe for healthy adults. Safety concerns come mainly from high-dose supplements, taking essential oils internally without medical guidance, allergies, pregnancy and interactions with medicines.
Can herbs interact with my medication?
Yes. St John's wort taken by mouth interacts with many drugs, including birth control, blood thinners and antidepressants. Chamomile may interact with warfarin. Always tell your doctor and pharmacist which herbs you use.
Can I use medicinal herbs during pregnancy?
Most herbs haven't been tested in pregnancy, and several, including dittany, sage and rosemary, are not recommended as remedies. Talk to your doctor or midwife before using any herb medicinally.
How much herbal tea can I drink a day?
For most herbal teas, 1 to 3 cups a day of about 1 to 2 g of dried herb per cup is a typical, sensible amount.
Greek medicinal herbs are best understood as a living tradition with a growing, uneven body of science behind it. Choose herbs with honest labels, use them for the mild, everyday problems they're suited to, and keep your doctor in the loop. Browse all our medicinal tea blends, or start with a sampler.
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Keep reading: Greek mountain tea benefits · Best herbs for gut health · Best herbs for sleep
Sources
- World Health Organization. WHO global report on traditional and complementary medicine 2019. Geneva: WHO; 2019.
- National Center for Complementary and Integrative Health. Using dietary supplements wisely.
- European Medicines Agency. Herbal medicinal products: well-established use and traditional use.
- European Medicines Agency, HMPC. Matricariae flos (chamomile flower): European Union herbal monograph.
- National Center for Complementary and Integrative Health. Chamomile. Updated November 2024.
- European Medicines Agency, HMPC. Lavandulae flos (lavender flower): Community herbal monograph, 2012.
- European Medicines Agency, HMPC. Melissae folium (lemon balm leaf): Community herbal monograph, 2013.
- National Center for Complementary and Integrative Health. Valerian. Updated May 2025.
- Alammar N, et al. The impact of peppermint oil on the irritable bowel syndrome: a meta-analysis of the pooled clinical data. BMC Complement Altern Med. 2019;19:21.
- Dabos KJ, Sfika E, Vlatta LJ, et al. Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. J Ethnopharmacol. 2010;127(2):205–209.
- European Medicines Agency, HMPC. Community herbal monograph on Origanum dictamnus L., herba. 2013.
- European Medicines Agency, HMPC. European Union herbal monograph on Sideritis spp., herba. 2016.
- European Medicines Agency, HMPC. Thymi herba (thyme): Community herbal monograph, 2014.
- European Medicines Agency, HMPC. European Union herbal monograph on Salvia officinalis L., folium, revision 1. 2015.
- European Medicines Agency, HMPC. Rosmarini folium (rosemary leaf): European Union herbal monograph, revision 1, 2024.
- Yang X, et al. Comparative efficacy and safety of Crocus sativus L. for treating mild to moderate major depressive disorder in adults: a meta-analysis of randomized controlled trials. Neuropsychiatr Dis Treat. 2018;14:1297–1305.
- European Medicines Agency, HMPC. European Union herbal monograph on Pistacia lentiscus L., resin (mastic). 2016.
- European Medicines Agency, HMPC. Hyperici herba (St John's wort), traditional use: European Union herbal monograph, revision 1, 2023.
- National Center for Complementary and Integrative Health. St. John's wort. Updated May 2025.
This article is for general information and is not medical advice. These statements have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure or prevent any disease. If you are pregnant, nursing, taking medication or have a medical condition, talk to your doctor first.